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MAPK/FoxA2-mediated cigarette smoke-induced squamous metaplasia of bronchial epithelial cells

OBJECTIVE: To explore the effect of cigarette smoke (CS) on the development of squamous metaplasia in human airway epithelial cells and the role of MAPK- and FoxA2-signaling pathways in the process. MATERIALS AND METHODS: In an in vitro study, we treated the bronchial epithelial cell line BEAS2B wit...

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Detalles Bibliográficos
Autores principales: Du, Chunling, Lu, Jinchang, Zhou, Lei, Wu, Bo, Zhou, Feng, Gu, Liang, Xu, Donghui, Sun, Yingxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701564/
https://www.ncbi.nlm.nih.gov/pubmed/29200841
http://dx.doi.org/10.2147/COPD.S143279