Pharmacodynamic testing and new validated HPLC method to assess the interchangeability between multi-source orlistat capsules

BACKGROUND: Orlistat is an irreversible inhibitor of the lipase enzyme that prevents trigylcerides from being digested, thereby inhibiting triglyceride hydrolysis and absorption. The resultant reduced calorie uptake enables a positive effect on weight control. Systemic absorption of the drug is, the...

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Detalles Bibliográficos
Autores principales: Zaid, Abdel Naser, Zohud, Nihal, E’layan, Bushra, Aburadi, Tasneem, Jaradat, Nidal, Ali, Iyad, Hussein, Fatima, Ghanem, Mashhour, Qaddomi, Aiman, Abu Zaaror, Yara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701567/
https://www.ncbi.nlm.nih.gov/pubmed/29200824
http://dx.doi.org/10.2147/DDDT.S138926

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