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Improved resection and prolonged overall survival with PD-1-IRDye800CW fluorescence probe-guided surgery and PD-1 adjuvant immunotherapy in 4T1 mouse model

An intraoperative technique to accurately identify microscopic tumor residuals could decrease the risk of positive surgical margins. Several lines of evidence support the expression and immunotherapeutic effect of PD-1 in breast cancer. Here, we sought to develop a fluorescence-labeled PD-1 probe fo...

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Detalles Bibliográficos
Autores principales: Du, Yang, Sun, Ting, Liang, Xiaolong, Li, Yuan, Jin, Zhengyu, Xue, Huadan, Wan, Yihong, Tian, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701610/
https://www.ncbi.nlm.nih.gov/pubmed/29200846
http://dx.doi.org/10.2147/IJN.S149235