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Expression of multidrug resistance protein P-glycoprotein in correlation with markers of hypoxia (HIF-1α, EPO, EPO-R) in invasive breast cancer with metastasis to lymph nodes

INTRODUCTION: Overexpression of the mdr-1 gene is the earliest discovered mechanism of multidrug resistance, which is associated with P-glycoprotein (P-gp) – a cell membrane protein responsible for the efflux of drugs of various structures out of cancer cells. Although the expression of P-glycoprote...

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Detalles Bibliográficos
Autores principales: Badowska-Kozakiewicz, Anna M., Sobol, Maria, Patera, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701689/
https://www.ncbi.nlm.nih.gov/pubmed/29181060
http://dx.doi.org/10.5114/aoms.2016.62723