Mitochondrial Respiration Is Reduced in Atherosclerosis, Promoting Necrotic Core Formation and Reducing Relative Fibrous Cap Thickness

OBJECTIVE—: Mitochondrial DNA (mtDNA) damage is present in murine and human atherosclerotic plaques. However, whether endogenous levels of mtDNA damage are sufficient to cause mitochondrial dysfunction and whether decreasing mtDNA damage and improving mitochondrial respiration affects plaque burden...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Emma P.K., Reinhold, Johannes, Yu, Haixiang, Starks, Lakshi, Uryga, Anna K., Foote, Kirsty, Finigan, Alison, Figg, Nichola, Pung, Yuh-Fen, Logan, Angela, Murphy, Michael P., Bennett, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Translational Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701734/
https://www.ncbi.nlm.nih.gov/pubmed/28970293
http://dx.doi.org/10.1161/ATVBAHA.117.310042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701734/
https://www.ncbi.nlm.nih.gov/pubmed/28970293
http://dx.doi.org/10.1161/ATVBAHA.117.310042

Ejemplares similares