Size, Shape, and Sequence-Dependent Immunogenicity of RNA Nanoparticles

RNA molecules have emerged as promising therapeutics. Like all other drugs, the safety profile and immune response are important criteria for drug evaluation. However, the literature on RNA immunogenicity has been controversial. Here, we used the approach of RNA nanotechnology to demonstrate that th...

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Detalles Bibliográficos
Autores principales: Guo, Sijin, Li, Hui, Ma, Mengshi, Fu, Jian, Dong, Yizhou, Guo, Peixuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701797/
https://www.ncbi.nlm.nih.gov/pubmed/29246318
http://dx.doi.org/10.1016/j.omtn.2017.10.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701797/
https://www.ncbi.nlm.nih.gov/pubmed/29246318
http://dx.doi.org/10.1016/j.omtn.2017.10.010

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