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Size, Shape, and Sequence-Dependent Immunogenicity of RNA Nanoparticles
RNA molecules have emerged as promising therapeutics. Like all other drugs, the safety profile and immune response are important criteria for drug evaluation. However, the literature on RNA immunogenicity has been controversial. Here, we used the approach of RNA nanotechnology to demonstrate that th...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701797/ https://www.ncbi.nlm.nih.gov/pubmed/29246318 http://dx.doi.org/10.1016/j.omtn.2017.10.010 |