Skin Delivery of Clec4a Small Hairpin RNA Elicited an Effective Antitumor Response by Enhancing CD8(+) Immunity In Vivo

Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. The present study investigated whether downregulating the expression of Clec4a via skin delivery of small hairpin RNA (shRNA) using a gene gun produced str...

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Detalles Bibliográficos
Autores principales: Weng, Tzu-Yang, Li, Chia-Jung, Li, Chung-Yen, Hung, Yu-Hsuan, Yen, Meng-Chi, Chang, Yu-Wei, Chen, Yu-Hung, Chen, Yi-Ling, Hsu, Hui-Ping, Chang, Jang-Yang, Lai, Ming-Derg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701806/
https://www.ncbi.nlm.nih.gov/pubmed/29246320
http://dx.doi.org/10.1016/j.omtn.2017.10.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701806/
https://www.ncbi.nlm.nih.gov/pubmed/29246320
http://dx.doi.org/10.1016/j.omtn.2017.10.015

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