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Mechanical confinement regulates cartilage matrix formation by chondrocytes

Cartilage tissue equivalents formed from hydrogels containing chondrocytes could provide a solution for replacing damaged cartilage. Previous approaches have often utilized elastic hydrogels. However, elastic stresses may restrict cartilage matrix formation and alter the chondrocyte phenotype. Here...

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Detalles Bibliográficos
Autores principales: Lee, Hong-pyo, Gu, Luo, Mooney, David J., Levenston, Marc E., Chaudhuri, Ovijit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701824/
https://www.ncbi.nlm.nih.gov/pubmed/28967913
http://dx.doi.org/10.1038/nmat4993