β1-Adrenergic Receptor Contains Multiple IA(k) and IE(k) Binding Epitopes That Induce T Cell Responses with Varying Degrees of Autoimmune Myocarditis in A/J Mice

Myocarditis/dilated cardiomyopathy (DCM) patients can develop autoantibodies to various cardiac antigens and one major antigen is β1-adrenergic receptor (β(1)AR). Previous reports indicate that animals immunized with a β(1)AR fragment encompassing, 197–222 amino acids for a prolonged period can deve...

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Detalles Bibliográficos
Autores principales: Basavalingappa, Rakesh H., Massilamany, Chandirasegaran, Krishnan, Bharathi, Gangaplara, Arunakumar, Rajasekaran, Rajkumar A., Afzal, Muhammad Z., Riethoven, Jean-Jack, Strande, Jennifer L., Steffen, David, Reddy, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701947/
https://www.ncbi.nlm.nih.gov/pubmed/29209317
http://dx.doi.org/10.3389/fimmu.2017.01567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701947/
https://www.ncbi.nlm.nih.gov/pubmed/29209317
http://dx.doi.org/10.3389/fimmu.2017.01567

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