Preparation, Evaluation and Bioavailability Studies of Eudragit Coated PLGA Nanoparticles for Sustained Release of Eluxadoline for the Treatment of Irritable Bowel Syndrome

Eluxadoline is a newly approved orally administered drug used for the treatment of Irritable Bowel Syndrome with Diarrhea. It is reported as a poorly water-soluble drug due to which its dissolution rate and oral bioavailability are very poor. In this work, various plain PLGA nanoparticles (NPs) (F1–...

Descripción completa

Detalles Bibliográficos
Autores principales: Anwer, Md. K., Al-Shdefat, Ramadan, Ezzeldin, Essam, Alshahrani, Saad M., Alshetaili, Abdullah S., Iqbal, Muzaffar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702012/
https://www.ncbi.nlm.nih.gov/pubmed/29209215
http://dx.doi.org/10.3389/fphar.2017.00844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702012/
https://www.ncbi.nlm.nih.gov/pubmed/29209215
http://dx.doi.org/10.3389/fphar.2017.00844

Ejemplares similares