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Endogenous signalling pathways and caged IP(3) evoke Ca(2+) puffs at the same abundant immobile intracellular sites
The building blocks of intracellular Ca(2+) signals evoked by inositol 1,4,5-trisphosphate receptors (IP(3)Rs) are Ca(2+) puffs, transient focal increases in Ca(2+) concentration that reflect the opening of small clusters of IP(3)Rs. We use total internal reflection fluorescence microscopy and autom...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Company of Biologists Ltd
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702060/ https://www.ncbi.nlm.nih.gov/pubmed/28893841 http://dx.doi.org/10.1242/jcs.208520 |