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Endogenous signalling pathways and caged IP(3) evoke Ca(2+) puffs at the same abundant immobile intracellular sites

The building blocks of intracellular Ca(2+) signals evoked by inositol 1,4,5-trisphosphate receptors (IP(3)Rs) are Ca(2+) puffs, transient focal increases in Ca(2+) concentration that reflect the opening of small clusters of IP(3)Rs. We use total internal reflection fluorescence microscopy and autom...

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Detalles Bibliográficos
Autores principales:	Keebler, Michael V., Taylor, Colin W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702060/ https://www.ncbi.nlm.nih.gov/pubmed/28893841 http://dx.doi.org/10.1242/jcs.208520

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