ENCoRE: an efficient software for CRISPR screens identifies new players in extrinsic apoptosis

BACKGROUND: As CRISPR/Cas9 mediated screens with pooled guide libraries in somatic cells become increasingly established, an unmet need for rapid and accurate companion informatics tools has emerged. We have developed a lightweight and efficient software to easily manipulate large raw next generatio...

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Detalles Bibliográficos
Autores principales: Trümbach, Dietrich, Pfeiffer, Susanne, Poppe, Manuel, Scherb, Hagen, Doll, Sebastian, Wurst, Wolfgang, Schick, Joel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702081/
https://www.ncbi.nlm.nih.gov/pubmed/29178829
http://dx.doi.org/10.1186/s12864-017-4285-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702081/
https://www.ncbi.nlm.nih.gov/pubmed/29178829
http://dx.doi.org/10.1186/s12864-017-4285-2

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