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ENCoRE: an efficient software for CRISPR screens identifies new players in extrinsic apoptosis
BACKGROUND: As CRISPR/Cas9 mediated screens with pooled guide libraries in somatic cells become increasingly established, an unmet need for rapid and accurate companion informatics tools has emerged. We have developed a lightweight and efficient software to easily manipulate large raw next generatio...
Autores principales: | Trümbach, Dietrich, Pfeiffer, Susanne, Poppe, Manuel, Scherb, Hagen, Doll, Sebastian, Wurst, Wolfgang, Schick, Joel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702081/ https://www.ncbi.nlm.nih.gov/pubmed/29178829 http://dx.doi.org/10.1186/s12864-017-4285-2 |
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