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MicroRNA-133 overexpression promotes the therapeutic efficacy of mesenchymal stem cells on acute myocardial infarction

BACKGROUND: Our study aim was to evaluate the therapeutic efficacy and mechanisms of miR-133-overexpressing mesenchymal stem cells (MSCs) on acute myocardial infarction. METHODS: Rat MSCs were isolated and purified by whole bone marrow adherent culturing. After transfection with the agomir or antago...

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Detalles Bibliográficos
Autores principales: Chen, Yueqiu, Zhao, Yunfeng, Chen, Weiqian, Xie, Lincen, Zhao, Zhen-Ao, Yang, Junjie, Chen, Yihuan, Lei, Wei, Shen, Zhenya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702098/
https://www.ncbi.nlm.nih.gov/pubmed/29178928
http://dx.doi.org/10.1186/s13287-017-0722-z