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Viral Cre-LoxP tools aid genome engineering in mammalian cells
BACKGROUND: Targeted nucleases have transformed genome editing technology, providing more efficient methods to make targeted changes in mammalian genome. In parallel, there is an increasing demand of Cre-LoxP technology for complex genome manipulation such as large deletion, addition, gene fusion an...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702101/ https://www.ncbi.nlm.nih.gov/pubmed/29204184 http://dx.doi.org/10.1186/s13036-017-0087-y |