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Viral Cre-LoxP tools aid genome engineering in mammalian cells

BACKGROUND: Targeted nucleases have transformed genome editing technology, providing more efficient methods to make targeted changes in mammalian genome. In parallel, there is an increasing demand of Cre-LoxP technology for complex genome manipulation such as large deletion, addition, gene fusion an...

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Detalles Bibliográficos
Autores principales:	Sengupta, Ranjita, Mendenhall, Amy, Sarkar, Nandita, Mukherjee, Chandreyee, Afshari, Amirali, Huang, Joseph, Lu, Biao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702101/ https://www.ncbi.nlm.nih.gov/pubmed/29204184 http://dx.doi.org/10.1186/s13036-017-0087-y

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