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Effects of IFN-γ coding plasmid supplementation in the immune response and protection elicited by Trypanosoma cruzi attenuated parasites

BACKGROUND: Previous studies showed that a naturally attenuated strain from Trypanosoma cruzi triggers an immune response mainly related to a Th2-type profile. Albeit this, a strong protection against virulent challenge was obtained after priming mice with this attenuated strain. However, this prote...

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Detalles Bibliográficos
Autores principales: Pérez Brandán, Cecilia, Mesías, Andrea C., Parodi, Cecilia, Cimino, Rubén O., Pérez Brandán, Carolina, Diosque, Patricio, Basombrío, Miguel Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702110/
https://www.ncbi.nlm.nih.gov/pubmed/29178839
http://dx.doi.org/10.1186/s12879-017-2834-6