Cargando…

Genome-wide segregation of single nucleotide and structural variants into single cancer cells

BACKGROUND: Single-cell genome sequencing provides high-resolution details of the clonal genomic modifications that occur during cancer initiation, progression, and ongoing evolution as patients undergo treatment. One limitation of current single-cell sequencing strategies is a suboptimal capacity t...

Descripción completa

Detalles Bibliográficos
Autores principales: Easton, John, Gonzalez-Pena, Veronica, Yergeau, Donald, Ma, Xiaotu, Gawad, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702214/
https://www.ncbi.nlm.nih.gov/pubmed/29178827
http://dx.doi.org/10.1186/s12864-017-4286-1