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Genome-wide segregation of single nucleotide and structural variants into single cancer cells

BACKGROUND: Single-cell genome sequencing provides high-resolution details of the clonal genomic modifications that occur during cancer initiation, progression, and ongoing evolution as patients undergo treatment. One limitation of current single-cell sequencing strategies is a suboptimal capacity t...

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Detalles Bibliográficos
Autores principales:	Easton, John, Gonzalez-Pena, Veronica, Yergeau, Donald, Ma, Xiaotu, Gawad, Charles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702214/ https://www.ncbi.nlm.nih.gov/pubmed/29178827 http://dx.doi.org/10.1186/s12864-017-4286-1

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