An Msh3 ATPase domain mutation has no effect on MMR function

OBJECTIVE: To demonstrate that the Msh3 ATPase domain is required for DNA mismatch repair and tumor suppression in a murine model. RESULTS: The DNA mismatch repair proteins are members of the ABC family of ATPases. ATP binding and hydrolysis regulates their mismatch repair function. In the current s...

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Detalles Bibliográficos
Autor principal: Edwards, Yasmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702223/
https://www.ncbi.nlm.nih.gov/pubmed/29178930
http://dx.doi.org/10.1186/s13104-017-2939-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702223/
https://www.ncbi.nlm.nih.gov/pubmed/29178930
http://dx.doi.org/10.1186/s13104-017-2939-4

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