VISPA2: a scalable pipeline for high-throughput identification and annotation of vector integration sites

BACKGROUND: Bioinformatics tools designed to identify lentiviral or retroviral vector insertion sites in the genome of host cells are used to address the safety and long-term efficacy of hematopoietic stem cell gene therapy applications and to study the clonal dynamics of hematopoietic reconstitutio...

Descripción completa

Detalles Bibliográficos
Autores principales: Spinozzi, Giulio, Calabria, Andrea, Brasca, Stefano, Beretta, Stefano, Merelli, Ivan, Milanesi, Luciano, Montini, Eugenio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702242/
https://www.ncbi.nlm.nih.gov/pubmed/29178837
http://dx.doi.org/10.1186/s12859-017-1937-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702242/
https://www.ncbi.nlm.nih.gov/pubmed/29178837
http://dx.doi.org/10.1186/s12859-017-1937-9

Ejemplares similares