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Identification of Antibody and Small Molecule Antagonists of Ferroportin-Hepcidin Interaction
The iron exporter ferroportin and its ligand, the hormone hepcidin, control fluxes of stored and recycled iron for use in a variety of essential biochemical processes. Inflammatory disorders and malignancies are often associated with high hepcidin levels, leading to ferroportin down-regulation, iron...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702341/ https://www.ncbi.nlm.nih.gov/pubmed/29209212 http://dx.doi.org/10.3389/fphar.2017.00838 |