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Identification of Antibody and Small Molecule Antagonists of Ferroportin-Hepcidin Interaction

The iron exporter ferroportin and its ligand, the hormone hepcidin, control fluxes of stored and recycled iron for use in a variety of essential biochemical processes. Inflammatory disorders and malignancies are often associated with high hepcidin levels, leading to ferroportin down-regulation, iron...

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Detalles Bibliográficos
Autores principales:	Ross, Sandra L., Biswas, Kaustav, Rottman, James, Allen, Jennifer R., Long, Jason, Miranda, Les P., Winters, Aaron, Arvedson, Tara L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702341/ https://www.ncbi.nlm.nih.gov/pubmed/29209212 http://dx.doi.org/10.3389/fphar.2017.00838

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