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World-wide distributions of lactase persistence alleles and the complex effects of recombination and selection

The genetic trait of lactase persistence (LP) is associated with at least five independent functional single nucleotide variants in a regulatory region about 14 kb upstream of the lactase gene [−13910*T (rs4988235), −13907*G (rs41525747), −13915*G (rs41380347), −14009*G (rs869051967) and −14010*C (r...

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Detalles Bibliográficos
Autores principales: Liebert, Anke, López, Saioa, Jones, Bryony Leigh, Montalva, Nicolas, Gerbault, Pascale, Lau, Winston, Thomas, Mark G., Bradman, Neil, Maniatis, Nikolas, Swallow, Dallas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702378/
https://www.ncbi.nlm.nih.gov/pubmed/29063188
http://dx.doi.org/10.1007/s00439-017-1847-y