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The Antifungal Plant Defensin HsAFP1 Is a Phosphatidic Acid-Interacting Peptide Inducing Membrane Permeabilization

HsAFP1, a plant defensin isolated from coral bells (Heuchera sanguinea), is characterized by broad-spectrum antifungal activity. Previous studies indicated that HsAFP1 binds to specific fungal membrane components, which had hitherto not been identified, and induces mitochondrial dysfunction and cell...

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Detalles Bibliográficos
Autores principales: Cools, Tanne L., Vriens, Kim, Struyfs, Caroline, Verbandt, Sara, Ramada, Marcelo H. S., Brand, Guilherme D., Bloch, Carlos, Koch, Barbara, Traven, Ana, Drijfhout, Jan W., Demuyser, Liesbeth, Kucharíková, Soňa, Van Dijck, Patrick, Spasic, Dragana, Lammertyn, Jeroen, Cammue, Bruno P. A., Thevissen, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702387/
https://www.ncbi.nlm.nih.gov/pubmed/29209301
http://dx.doi.org/10.3389/fmicb.2017.02295