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Apoptotic Signaling Pathways in Glioblastoma and Therapeutic Implications

Glioblastoma multiforme (GBM) is the most hostile type of brain cancer. Its aggressiveness is due to increased invasion, migration, proliferation, angiogenesis, and a decreased apoptosis. In this review, we discuss the role of key regulators of apoptosis in GBM and glioblastoma stem cells. Given the...

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Detalles Bibliográficos
Autores principales: Valdés-Rives, Silvia Anahi, Casique-Aguirre, Diana, Germán-Castelán, Liliana, Velasco-Velázquez, Marco A., González-Arenas, Aliesha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702396/
https://www.ncbi.nlm.nih.gov/pubmed/29259986
http://dx.doi.org/10.1155/2017/7403747