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CYLD Deubiquitinase Negatively Regulates High Glucose-Induced NF-κB Inflammatory Signaling in Mesangial Cells

Nuclear factor-kappa B (NF-κB) is the key part of multiple signal transduction of inflammation in the pathogenesis of diabetic nephropathy (DN). The ubiquitin-proteasome system is extensively involved in the regulation of the NF-κB pathway. Cylindromatosis (CYLD) has deubiquitinase activity and acts...

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Detalles Bibliográficos
Autores principales: Li, Yanhui, Huang, Wei, Xu, Youhua, Zhou, Luping, Liang, Yaling, Gao, Chenlin, Long, Yang, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702419/
https://www.ncbi.nlm.nih.gov/pubmed/29259980
http://dx.doi.org/10.1155/2017/3982906