An update on anticancer drug development and delivery targeting carbonic anhydrase IX

The expression of carbonic anhydrase (CA) IX is up-regulated in many types of solid tumors in humans under hypoxic and acidic microenvironment. Inhibition of CA IX enzymatic activity with selective inhibitors, antibodies or labeled probes has been shown to reverse the acidic environment of solid tum...

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Detalles Bibliográficos
Autores principales: Kazokaitė, Justina, Aspatwar, Ashok, Parkkila, Seppo, Matulis, Daumantas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702504/
https://www.ncbi.nlm.nih.gov/pubmed/29181278
http://dx.doi.org/10.7717/peerj.4068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702504/
https://www.ncbi.nlm.nih.gov/pubmed/29181278
http://dx.doi.org/10.7717/peerj.4068

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