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Mutations in fetal genes involved in innate immunity and host defense against microbes increase risk of preterm premature rupture of membranes (PPROM)

BACKGROUND: Twin studies have revealed a significant contribution of the fetal genome to risk of preterm birth. Preterm premature rupture of membranes (PPROM) is the leading identifiable cause of preterm delivery. Infection and inflammation of the fetal membranes is commonly found associated with PP...

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Detalles Bibliográficos
Autores principales: Modi, Bhavi P., Teves, Maria E., Pearson, Laurel N., Parikh, Hardik I., Haymond‐Thornburg, Hannah, Tucker, John L., Chaemsaithong, Piya, Gomez‐Lopez, Nardhy, York, Timothy P., Romero, Roberto, Strauss, Jerome F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702565/
https://www.ncbi.nlm.nih.gov/pubmed/29178652
http://dx.doi.org/10.1002/mgg3.330