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A protein interaction mechanism for suppressing the mechanosensitive Piezo channels

Piezo proteins are bona fide mammalian mechanotransduction channels for various cell types including endothelial cells. The mouse Piezo1 of 2547 residues forms a three-bladed, propeller-like homo-trimer comprising a central pore-module and three propeller-structures that might serve as mechanotransd...

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Detalles Bibliográficos
Autores principales: Zhang, Tingxin, Chi, Shaopeng, Jiang, Fan, Zhao, Qiancheng, Xiao, Bailong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702604/
https://www.ncbi.nlm.nih.gov/pubmed/29176668
http://dx.doi.org/10.1038/s41467-017-01712-z