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Targeting TRIM5α in HIV Cure Strategies for the CRISPR-Cas9 Era

In the past decade, studies of innate immune activity against HIV-1 and other retroviruses have revealed a powerful array of host factors that can attack the virus at various stages of its life cycle in human and primate cells, raising the prospect that these antiviral factors could be manipulated i...

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Detalles Bibliográficos
Autores principales: Weatherley, Daryl Anne Victoria, Boswell, Michael Terence, Rowland-Jones, Sarah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702620/
https://www.ncbi.nlm.nih.gov/pubmed/29213273
http://dx.doi.org/10.3389/fimmu.2017.01616