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Revealing the Complexity in CD8 T Cell Responses to Infection in Inbred C57B/6 versus Outbred Swiss Mice

Recent work has suggested that current mouse models may underrepresent the complexity of human immune responses. While most mouse immunology studies utilize inbred mouse strains, it is unclear if conclusions drawn from inbred mice can be extended to all mouse strains or generalized to humans. We rec...

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Detalles Bibliográficos
Autores principales: Martin, Matthew D., Danahy, Derek B., Hartwig, Stacey M., Harty, John T., Badovinac, Vladimir P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702636/
https://www.ncbi.nlm.nih.gov/pubmed/29213267
http://dx.doi.org/10.3389/fimmu.2017.01527