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EZH2-mediated upregulation of ROS1 oncogene promotes oral cancer metastasis

Current anti-epidermal growth factor receptor (EGFR) therapy for oral cancer does not provide satisfactory efficacy due to drug resistance or reduced EGFR level. As an alternative candidate target for therapy, here we identified an oncogene, ROS1, as an important driver for oral squamous cell carcin...

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Detalles Bibliográficos
Autores principales: Shih, C-H, Chang, Y-J, Huang, W-C, Jang, T-H, Kung, H-J, Wang, W-C, Yang, M-H, Lin, M-C, Huang, S-F, Chou, S-W, Chang, E, Chiu, H, Shieh, T-Y, Chen, Y-J, Wang, L-H, Chen, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702718/
https://www.ncbi.nlm.nih.gov/pubmed/28759046
http://dx.doi.org/10.1038/onc.2017.262