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Exact sequence variants should replace operational taxonomic units in marker-gene data analysis

Recent advances have made it possible to analyze high-throughput marker-gene sequencing data without resorting to the customary construction of molecular operational taxonomic units (OTUs): clusters of sequencing reads that differ by less than a fixed dissimilarity threshold. New methods control err...

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Detalles Bibliográficos
Autores principales: Callahan, Benjamin J, McMurdie, Paul J, Holmes, Susan P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702726/
https://www.ncbi.nlm.nih.gov/pubmed/28731476
http://dx.doi.org/10.1038/ismej.2017.119