Assessing Pharmacodynamic Interactions in Mice Using the Multistate Tuberculosis Pharmacometric and General Pharmacodynamic Interaction Models

The aim of this study was to investigate pharmacodynamic (PD) interactions in mice infected with Mycobacterium tuberculosis using population pharmacokinetics (PKs), the Multistate Tuberculosis Pharmacometric (MTP) model, and the General Pharmacodynamic Interaction (GPDI) model. Rifampicin, isoniazid...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Chunli, Wicha, Sebastian G., de Knegt, Gerjo J., Ortega, Fatima, Alameda, Laura, Sousa, Veronica, de Steenwinkel, Jurriaan E. M., Simonsson, Ulrika S. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702905/
https://www.ncbi.nlm.nih.gov/pubmed/28657202
http://dx.doi.org/10.1002/psp4.12226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702905/
https://www.ncbi.nlm.nih.gov/pubmed/28657202
http://dx.doi.org/10.1002/psp4.12226

Ejemplares similares