Cargando…

Assessing Pharmacodynamic Interactions in Mice Using the Multistate Tuberculosis Pharmacometric and General Pharmacodynamic Interaction Models

The aim of this study was to investigate pharmacodynamic (PD) interactions in mice infected with Mycobacterium tuberculosis using population pharmacokinetics (PKs), the Multistate Tuberculosis Pharmacometric (MTP) model, and the General Pharmacodynamic Interaction (GPDI) model. Rifampicin, isoniazid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Chunli, Wicha, Sebastian G., de Knegt, Gerjo J., Ortega, Fatima, Alameda, Laura, Sousa, Veronica, de Steenwinkel, Jurriaan E. M., Simonsson, Ulrika S. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702905/ https://www.ncbi.nlm.nih.gov/pubmed/28657202 http://dx.doi.org/10.1002/psp4.12226

Ejemplares similares

The multistate tuberculosis pharmacometric model: a semi-mechanistic pharmacokinetic-pharmacodynamic model for studying drug effects in an acute tuberculosis mouse model
por: Chen, Chunli, et al.
Publicado: (2017)

A model-informed preclinical approach for prediction of clinical pharmacodynamic interactions of anti-TB drug combinations
por: Clewe, Oskar, et al.
Publicado: (2018)

A general pharmacodynamic interaction model identifies perpetrators and victims in drug interactions
por: Wicha, Sebastian G., et al.
Publicado: (2017)

Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies
por: Alffenaar, Jan-Willem C., et al.
Publicado: (2022)

Application of the Multistate Tuberculosis Pharmacometric Model in Patients With Rifampicin‐Treated Pulmonary Tuberculosis
por: Svensson, RJ, et al.
Publicado: (2016)

A multistate tuberculosis pharmacometric model: a framework for studying anti-tubercular drug effects in vitro
por: Clewe, Oskar, et al.
Publicado: (2016)

Improving treatment outcome assessment in a mouse tuberculosis model
por: Mourik, Bas C., et al.
Publicado: (2018)

Pharmacokinetics and Pharmacodynamics of Tedizolid
por: Iqbal, Khalid, et al.
Publicado: (2022)

Optimized Rhombic Experimental Dynamic Checkerboard Designs to Elucidate Pharmacodynamic Drug Interactions of Antibiotics
por: Kroemer, Niklas, et al.
Publicado: (2022)

Exploring Differences in Pharmacometrics of Rabeprazole between Genders via Population Pharmacokinetic–Pharmacodynamic Modeling
por: Jeong, Seung-Hyun, et al.
Publicado: (2023)

Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin
por: Keutzer, Lina, et al.
Publicado: (2022)

The interaction between prognostic and pharmacodynamic biomarkers
por: Bouranis, L, et al.
Publicado: (2013)

The Overview on the Pharmacokinetic and Pharmacodynamic Interactions of Triazoles
por: Czyrski, Andrzej, et al.
Publicado: (2021)

A review of pharmacokinetic and pharmacodynamic interactions with antipsychotics
por: Wijesinghe, Ruki
Publicado: (2016)

Mobile Health Apps for Improvement of Tuberculosis Treatment: Descriptive Review
por: Keutzer, Lina, et al.
Publicado: (2020)

Determination of the Pharmacokinetics and Pharmacodynamics of Isoniazid, Rifampicin, Pyrazinamide and Ethambutol in a Cross-Over Cynomolgus Macaque Model of Mycobacterium tuberculosis Infection
por: Sibley, Laura, et al.
Publicado: (2022)

Atazanavir–bilirubin interaction: a pharmacokinetic–pharmacodynamic model
por: Lozano, Roberto, et al.
Publicado: (2013)

Review of Tolvaptan’s Pharmacokinetic and Pharmacodynamic Properties and Drug Interactions
por: Bhatt, Purav R., et al.
Publicado: (2014)

Molecular and pharmacodynamic interactions between caffeine and dopaminergic system
por: Voiculescu, M, et al.
Publicado: (2014)

Pharmacology: The Pharmacodynamics of Nutrients and Nutrient Interactions in Biological Functions
por: Mohajeri, M. Hasan, et al.
Publicado: (2015)

Comorbid epilepsy and depression—pharmacokinetic and pharmacodynamic drug interactions
por: Miziak, Barbara, et al.
Publicado: (2022)

Mycobacterium tuberculosis clinical isolates of the Beijing and East-African Indian lineage induce fundamentally different host responses in mice compared to H37Rv
por: Mourik, Bas C., et al.
Publicado: (2019)

Improved power for TB Phase IIa trials using a model-based pharmacokinetic–pharmacodynamic approach compared with commonly used analysis methods
por: Svensson, Robin J., et al.
Publicado: (2017)

Cycloserine Population Pharmacokinetics and Pharmacodynamics in Patients with Tuberculosis
por: Alghamdi, Wael A., et al.
Publicado: (2019)

Drug Susceptibility of Mycobacterium tuberculosis Beijing Genotype and Association with MDR TB
por: de Steenwinkel, Jurriaan E.M., et al.
Publicado: (2012)

Pharmacodynamic and Pharmacokinetic Interactions of Propranolol with Garlic (Allium sativum) in Rats
por: Asdaq, Syed Mohammed Basheeruddin, et al.
Publicado: (2011)

Calcitriol in Combination Therapy for Prostate Cancer: Pharmacokinetic and Pharmacodynamic Interactions
por: Ben-Eltriki, Mohamed, et al.
Publicado: (2016)

Atazanavir–bilirubin interaction: a pharmacokinetic–pharmacodynamic model [Corrigendum]
Publicado: (2013)

Elucidating pharmacodynamic interaction of silver nanoparticle - topical deliverable antibiotics
por: Thirumurugan, G., et al.
Publicado: (2016)

Interaction of p-synephrine on the pharmacodynamics and pharmacokinetics of gliclazide in animal models
por: Vatsavai, Leela Krishna, et al.
Publicado: (2018)

Pharmacokinetic and pharmacodynamic interaction of Rosuvastatin calcium with guggulipid extract in rats
por: Asad, Mohammed, et al.
Publicado: (2021)

Oxycodone-Related Deaths: The Significance of Pharmacokinetic and Pharmacodynamic Drug Interactions
por: Jakobsson, Gerd, et al.
Publicado: (2022)

Pharmacokinetic and Pharmacodynamic Drug–Drug Interactions: Research Methods and Applications
por: Sun, Lei, et al.
Publicado: (2023)

Pharmacodynamics in hypothermia
por: Tveita, Torkjel
Publicado: (2012)

Systematic Prediction of Pharmacodynamic Drug-Drug Interactions through Protein-Protein-Interaction Network
por: Huang, Jialiang, et al.
Publicado: (2013)

Pharmacodynamic Parameters of Pharmacokinetic/Pharmacodynamic (PK/PD) Integration Models
por: Zhang, Longfei, et al.
Publicado: (2022)

Integrating Pharmacokinetics and Pharmacodynamics in Operational Research to End Tuberculosis
por: Alffenaar, Jan-Willem C, et al.
Publicado: (2020)

Reproducibility in pharmacometrics applied in a phase III trial of BCG-vaccination for COVID-19
por: van Wijk, Rob C., et al.
Publicado: (2023)

Multistate model for pharmacometric analyses of overall survival in HER2‐negative breast cancer patients treated with docetaxel
por: Krishnan, Sreenath M., et al.
Publicado: (2021)

Absence of Pharmacokinetic and Pharmacodynamic Interactions between Almorexant and Warfarin in Healthy Subjects
por: Dingemanse, Jasper, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_tb1dglue05t37ckt6ks9qeotgu