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Conserved roles for murine DUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons

To better understand transcriptional regulation during human oogenesis and pre-implantation development, we defined stage-specific transcription, which revealed the cleavage stage as highly distinctive. Here, we present multiple lines of evidence that a eutherian-specific, multi-copy retrogene, DUX4...

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Detalles Bibliográficos
Autores principales: Hendrickson, Peter G., Doráis, Jessie A., Grow, Edward J., Whiddon, Jennifer L., Lim, Jong-Won, Wike, Candice L., Weaver, Bradley D., Pflueger, Christian, Emery, Benjamin R., Wilcox, Aaron L., Nix, David A., Peterson, C. Matthew, Tapscott, Stephen J., Carrell, Douglas T., Cairns, Bradley R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703070/
https://www.ncbi.nlm.nih.gov/pubmed/28459457
http://dx.doi.org/10.1038/ng.3844