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Simultaneous overexpression of miR-126 and miR-34a induces a superior antitumor efficacy in pancreatic adenocarcinoma

BACKGROUND: Pancreatic adenocarcinoma (PAC) is one of the most fatal cancers due to its high degree of malignancy, increasing incidence, high mortality, and unsatisfactory treatment efficacy. Evidence has suggested that numerous microRNAs (miRNAs), including miR-126 and miR-34a, have potent tumor-su...

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Detalles Bibliográficos
Autores principales: Feng, Shu-De, Mao, Ziming, Liu, Chunying, Nie, Yu-Song, Sun, Bin, Guo, Minggao, Su, Changqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703150/
https://www.ncbi.nlm.nih.gov/pubmed/29200874
http://dx.doi.org/10.2147/OTT.S149632