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Andrographolide enhanced 5-fluorouracil-induced antitumor effect in colorectal cancer via inhibition of c-MET pathway

Colorectal cancer (CRC) is the third most common malignant neoplasm worldwide. 5-Fluorouracil (5-Fu) is the most important chemotherapeutic drug used for the treatment of CRC. However, resistance to 5-Fu therapies is a growing concern in CRC clinical practice recently. Andrographolide (Andro) is a m...

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Detalles Bibliográficos
Autores principales: Su, Meng, Qin, Baoli, Liu, Fang, Chen, Yuze, Zhang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703152/
https://www.ncbi.nlm.nih.gov/pubmed/29200829
http://dx.doi.org/10.2147/DDDT.S140354