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TNF superfamily member APRIL enhances midbrain dopaminergic axon growth and contributes to the nigrostriatal projection in vivo

We have studied the role of the tumor necrosis factor superfamily member APRIL in the development of embryonic mouse midbrain dopaminergic neurons in vitro and in vivo. In culture, soluble APRIL enhanced axon growth during a window of development between E12 and E14 when nigrostriatal axons are grow...

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Detalles Bibliográficos
Autores principales: McWilliams, Thomas G., Howard, Laura, Wyatt, Sean, Davies, Alun M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703168/
https://www.ncbi.nlm.nih.gov/pubmed/28911883
http://dx.doi.org/10.1016/j.expneurol.2017.09.007