RKIP reduction enhances radioresistance by activating the Shh signaling pathway in non-small-cell lung cancer

Non-small-cell lung cancer (NSCLC) is exceptionally deadly because the tumors lack sensitive early-stage diagnostic biomarkers and are resistant to radiation and chemotherapy. Here, we investigated the role and mechanism of Raf kinase inhibitory protein (RKIP) in NSCLC radioresistance. The clinical...

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Detalles Bibliográficos
Autores principales: Xie, Shi-Yang, Li, Guang, Han, Chong, Yu, Yang-Yang, Li, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703172/
https://www.ncbi.nlm.nih.gov/pubmed/29200875
http://dx.doi.org/10.2147/OTT.S149200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703172/
https://www.ncbi.nlm.nih.gov/pubmed/29200875
http://dx.doi.org/10.2147/OTT.S149200

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