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RKIP reduction enhances radioresistance by activating the Shh signaling pathway in non-small-cell lung cancer
Non-small-cell lung cancer (NSCLC) is exceptionally deadly because the tumors lack sensitive early-stage diagnostic biomarkers and are resistant to radiation and chemotherapy. Here, we investigated the role and mechanism of Raf kinase inhibitory protein (RKIP) in NSCLC radioresistance. The clinical...
Autores principales: | Xie, Shi-Yang, Li, Guang, Han, Chong, Yu, Yang-Yang, Li, Nan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703172/ https://www.ncbi.nlm.nih.gov/pubmed/29200875 http://dx.doi.org/10.2147/OTT.S149200 |
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