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Conditioning on future exposure to define study cohorts can induce bias: the case of low-dose acetylsalicylic acid and risk of major bleeding

BACKGROUND: A principle of cohort studies is that cohort membership is defined by current rather than future exposure information. Pharmacoepidemiologic studies using existing databases are vulnerable to violation of this principle. We evaluated the impact of using data on future redemption of presc...

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Detalles Bibliográficos
Autores principales: Lund, Jennifer L, Horváth-Puhó, Erzsébet, Komjáthiné Szépligeti, Szimonetta, Sørensen, Henrik Toft, Pedersen, Lars, Ehrenstein, Vera, Stürmer, Til
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703173/
https://www.ncbi.nlm.nih.gov/pubmed/29200891
http://dx.doi.org/10.2147/CLEP.S147175