Mutation of nucleotides around the +1 position of type 3 polymerase III promoters: The effect on transcriptional activity and start site usage

Type 3 RNA polymerase III (Pol III) promoters are widely used for the expression of small RNAs such as short hairpin RNA and guide RNA in the popular RNAi and CRISPR-Cas gene regulation systems. Although it is generally believed that type 3 Pol III promoters use a defined transcription start site (+...

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Detalles Bibliográficos
Autores principales: Gao, Zongliang, Harwig, Alex, Berkhout, Ben, Herrera-Carrillo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703244/
https://www.ncbi.nlm.nih.gov/pubmed/28598252
http://dx.doi.org/10.1080/21541264.2017.1322170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703244/
https://www.ncbi.nlm.nih.gov/pubmed/28598252
http://dx.doi.org/10.1080/21541264.2017.1322170

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