Cargando…

Peptidyl arginine deiminase immunization induces anticitrullinated protein antibodies in mice with particular MHC types

Autoantibodies to citrullinated proteins (ACPAs) are present in two-thirds of patients with rheumatoid arthritis (RA). ACPAs are produced in the absence of identified T cell responses for each citrullinated protein. Peptidyl arginine deiminase 4 (PAD4), which binds proteins and citrullinates them, i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Arnoux, Fanny, Mariot, Charlotte, Peen, Elisa, Lambert, Nathalie C., Balandraud, Nathalie, Roudier, Jean, Auger, Isabelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2017
Materias:	PNAS Plus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703315/ https://www.ncbi.nlm.nih.gov/pubmed/29109281 http://dx.doi.org/10.1073/pnas.1713112114

Ejemplares similares

Peptidylarginine Deiminase Autoimmunity and the Development of Anti–Citrullinated Protein Antibody in Rheumatoid Arthritis: The Hapten–Carrier Model
por: Auger, Isabelle, et al.
Publicado: (2020)

A rigorous method for multigenic families' functional annotation: the peptidyl arginine deiminase (PADs) proteins family example
por: Balandraud, N, et al.
Publicado: (2005)

Arginine methylation is required for canonical Wnt signaling and endolysosomal trafficking
por: Albrecht, Lauren V., et al.
Publicado: (2018)

Isolation and characterization of NY-ESO-1–specific T cell receptors restricted on various MHC molecules
por: Bethune, Michael T., et al.
Publicado: (2018)

MHC-mismatched mixed chimerism restores peripheral tolerance of noncross-reactive autoreactive T cells in NOD mice
por: Zhang, Mingfeng, et al.
Publicado: (2018)

B cell receptor ligation induces display of V-region peptides on MHC class II molecules to T cells
por: Huszthy, Peter Csaba, et al.
Publicado: (2019)

Discovery of Novel Potential Reversible Peptidyl Arginine Deiminase Inhibitor
por: Aliko, Ardita, et al.
Publicado: (2019)

Entrainment of mammalian motile cilia in the brain with hydrodynamic forces
por: Pellicciotta, Nicola, et al.
Publicado: (2020)

Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function
por: Rengachari, Srinivasan, et al.
Publicado: (2018)

Peptidyl Arginine Deiminase 2 (PADI2)-Mediated Arginine Citrullination Modulates Transcription in Cancer
por: Beato, Miguel, et al.
Publicado: (2020)

A complete phylogenetic analysis coupling expression data from EST databases. An example with a family of genes: the peptidyl arginine deiminase genes
por: Balandraud, N, et al.
Publicado: (2005)

New autoantibodies in early rheumatoid arthritis
por: Charpin, Caroline, et al.
Publicado: (2013)

Structural basis for the role of serine-rich repeat proteins from Lactobacillus reuteri in gut microbe–host interactions
por: Sequeira, Saannya, et al.
Publicado: (2018)

Failure to eliminate a phosphorylated glucose analog leads to neutropenia in patients with G6PT and G6PC3 deficiency
por: Veiga-da-Cunha, Maria, et al.
Publicado: (2019)

Axogenic mechanism enhances retinal ganglion cell excitability during early progression in glaucoma
por: Risner, Michael L., et al.
Publicado: (2018)

Peptidyl Arginine Deiminase Type 4 Gene Promoter Hypo-Methylation in Rheumatoid Arthritis
por: Kolarz, Bogdan, et al.
Publicado: (2020)

Implications of Porphyromonas gingivalis peptidyl arginine deiminase and gingipain R in human health and diseases
por: Chow, Yoke Chan, et al.
Publicado: (2022)

Expression of Peptidyl Arginine Deiminase 2 Is Closely Associated with Recurrence in Patients with Hepatocellular Carcinoma
por: Uhm, Sunho, et al.
Publicado: (2023)

Pleiotropic effects for Parkin and LRRK2 in leprosy type-1 reactions and Parkinson’s disease
por: Fava, Vinicius M., et al.
Publicado: (2019)

Inhibition of HDAC3 reverses Alzheimer’s disease-related pathologies in vitro and in the 3xTg-AD mouse model
por: Janczura, Karolina J., et al.
Publicado: (2018)

Coupled European and Greenland last glacial dust activity driven by North Atlantic climate
por: Újvári, Gábor, et al.
Publicado: (2017)

Regulatory changes in pterin and carotenoid genes underlie balanced color polymorphisms in the wall lizard
por: Andrade, Pedro, et al.
Publicado: (2019)

Unrestrained markerless trait stacking in Nannochloropsis gaditana through combined genome editing and marker recycling technologies
por: Verruto, John, et al.
Publicado: (2018)

Chronic social stress-induced hyperglycemia in mice couples individual stress susceptibility to impaired spatial memory
por: van der Kooij, Michael A., et al.
Publicado: (2018)

Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration
por: Pristerà, Alessandro, et al.
Publicado: (2019)

M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer’s disease genes and improving memory
por: Volmar, Claude-Henry, et al.
Publicado: (2017)

Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA
por: Ferron, François, et al.
Publicado: (2018)

Activated integrins identify functional antigen-specific CD8(+) T cells within minutes after antigen stimulation
por: Dimitrov, Stoyan, et al.
Publicado: (2018)

A rapid ELISA based method to determine peptidyl-arginine deiminase activity in biological samples
por: Nijenhuis, S, et al.
Publicado: (2003)

Inhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis
por: Moscarello, Mario A., et al.
Publicado: (2013)

Association of anti-peptidyl arginine deiminase antibodies with radiographic severity of rheumatoid arthritis in African Americans
por: Navarro-Millán, Iris, et al.
Publicado: (2016)

Neutrophils prevent rectal bleeding in ulcerative colitis by peptidyl-arginine deiminase-4-dependent immunothrombosis
por: Leppkes, Moritz, et al.
Publicado: (2022)

Porphyromonas gingivalis Peptidyl Arginine Deiminase (PPAD) in the Context of the Feed-Forward Loop of Inflammation in Periodontitis
por: Prucsi, Zsombor, et al.
Publicado: (2023)

Phosphatases control PKA-dependent functional microdomains at the outer mitochondrial membrane
por: Burdyga, Alex, et al.
Publicado: (2018)

How RA Associated HLA-DR Molecules Contribute to the Development of Antibodies to Citrullinated Proteins: The Hapten Carrier Model
por: Roudier, Jean, et al.
Publicado: (2022)

Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation
por: Gehrmann, Ulf, et al.
Publicado: (2019)

Robust nanoscopy of a synaptic protein in living mice by organic-fluorophore labeling
por: Masch, Jennifer-Magdalena, et al.
Publicado: (2018)

Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti–PD-1 treatment
por: Peranzoni, Elisa, et al.
Publicado: (2018)

Weevil pgrp-lb prevents endosymbiont TCT dissemination and chronic host systemic immune activation
por: Maire, Justin, et al.
Publicado: (2019)

Cooption of the pteridine biosynthesis pathway underlies the diversification of embryonic colors in water striders
por: Vargas-Lowman, Aidamalia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_rlghil7845sfnoeurmeam74pds