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Proof of region-specific multipotent progenitors in human breast epithelia

The human breast parenchyma consists of collecting ducts and terminal duct lobular units (TDLUs). The TDLU is the site of origin of most breast cancers. The reason for such focal susceptibility to cancer remains poorly understood. Here, we take advantage of a region-specific heterogeneity in luminal...

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Detalles Bibliográficos
Autores principales: Fridriksdottir, Agla J., Villadsen, René, Morsing, Mikkel, Klitgaard, Marie Christine, Kim, Jiyoung, Petersen, Ole William, Rønnov-Jessen, Lone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703323/
https://www.ncbi.nlm.nih.gov/pubmed/29109259
http://dx.doi.org/10.1073/pnas.1714063114