Metabolic control of regulatory T cell (Treg) survival and function by Lkb1

The metabolic programs of functionally distinct T cell subsets are tailored to their immunologic activities. While quiescent T cells use oxidative phosphorylation (OXPHOS) for energy production, and effector T cells (Teffs) rely on glycolysis for proliferation, the distinct metabolic features of reg...

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Detalles Bibliográficos
Autores principales: He, Nanhai, Fan, Weiwei, Henriquez, Brian, Yu, Ruth T., Atkins, Annette R., Liddle, Christopher, Zheng, Ye, Downes, Michael, Evans, Ronald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703326/
https://www.ncbi.nlm.nih.gov/pubmed/29109251
http://dx.doi.org/10.1073/pnas.1715363114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703326/
https://www.ncbi.nlm.nih.gov/pubmed/29109251
http://dx.doi.org/10.1073/pnas.1715363114

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