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Metabolic control of regulatory T cell (Treg) survival and function by Lkb1
The metabolic programs of functionally distinct T cell subsets are tailored to their immunologic activities. While quiescent T cells use oxidative phosphorylation (OXPHOS) for energy production, and effector T cells (Teffs) rely on glycolysis for proliferation, the distinct metabolic features of reg...
Autores principales: | He, Nanhai, Fan, Weiwei, Henriquez, Brian, Yu, Ruth T., Atkins, Annette R., Liddle, Christopher, Zheng, Ye, Downes, Michael, Evans, Ronald M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703326/ https://www.ncbi.nlm.nih.gov/pubmed/29109251 http://dx.doi.org/10.1073/pnas.1715363114 |
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